FRIO Coolers – Insulated EpiPen Case for Safe Travel
Travelling somewhere warm with your epinephrine auto‑injector? FRIO Coolers are the original insulated epipen case that keeps your adrenaline pens in a safe temperature range even in hot climates. They work without ice or electricity, so you can carry your medication confidently on planes, at the beach, or on city breaks.
Key Features & Benefits
Temperature control: Maintains a safe range of approximately 18–26°C (64.4–78.8°F) for at least 45 hours, even when the ambient temperature reaches 37.8°C (100°F).
Drug‑free cooling technology: Water‑activated crystals in the inner poly‑cotton FRIO wallet provide evaporative cooling around your pens.
Reusable and durable: Designed as a long‑lasting insulated epipen case that can be reactivated over and over with water.
Easy to use: Submerge the FRIO wallet in cold water for around 5–10 minutes, gently dry with a paper towel, then insert your medication.
Versatile medication cooling wallet: Suitable for epinephrine auto‑injectors plus insulin pens, Humira, Enbrel and other temperature‑sensitive medicines.
Lightweight for travel: No ice packs or power required, making it ideal for flights, road trips, school, work and outdoor adventures.
Multiple colours: Available in black, blue, purple, red, green and burgundy to match your style or help family members tell cases apart.
Perfect for
People with severe allergies who need a reliable frio epipen case for warm weather and travel.
Families travelling with children who carry EPIPEN, Anapen, Jext, Auvi‑Q or Allerject auto‑injectors.
Travellers managing diabetes, rheumatoid arthritis or Crohn’s disease who use insulin, Humira or Enbrel pens.
Holiday, school or work trips where access to a fridge is limited but medication must stay within safe temperatures.
For extra travel peace of mind, pair your FRIO wallet with travel size medicine bottles for liquid antihistamine and kids travel wristbands printed with “Emergency” in multiple languages for international trips.
Product specifications
Sizes and capacity
Small FRIO Coolers – Insulated EpiPen Case
Adrenaline: 1 EPIPEN, Anapen, Jext, Auvi‑Q or Allerject.
Size: 21.6 cm (H) x 10.9 cm (W).
Rheumatoid arthritis / Crohn’s: 1 Humira pen or up to 2 Enbrel pens.
Diabetes: 2 standard insulin pens, or 1 insulin pen plus 2 x 3 ml cartridges.
FRIO Grande Coolers – Insulated EpiPen Case
Adrenaline: Up to 2 EPIPEN, Anapen, Jext, or 2 Auvi‑Q or Allerject auto‑injectors.
Size: 11.5 cm (H) x 26 cm (W).
Diabetes: 2 Bydureon pens.
Closure: Zipped outer wallet for added security.
Large FRIO Coolers – Insulated EpiPen Case
Adrenaline: 3 EPIPEN, Anapen, Jext, or 2 Auvi‑Q or Allerject auto‑injectors.
Size: 22.9 cm (H) x 16.5 cm (W) x 0.8 cm (D).
Rheumatoid arthritis / Crohn’s: Up to 3 Humira pens or up to 4 Enbrel pens.
Diabetes: 5 standard insulin pens; or 1 pen plus 10 x 3 ml cartridges; or 1 pen plus 15 x 1.5 ml cartridges; or 2 pens plus 6 x 3 ml cartridges.
Materials
Inner FRIO wallet: Poly‑cotton fabric with polymer cooling crystals.
Outer wallet: Non‑woven polyester protective cover (Grande includes zip closure).
Quality and safety
Designed originally for insulin but suitable for a wide range of temperature‑sensitive medicines, including adrenaline auto‑injectors.
For metal pens, electronic timing devices or accessories with electronic components, use a waterproof liner inside the FRIO to protect against moisture.
Follow activation instructions carefully: Do not over‑soak, as excess water can cause the wallet to swell; allow to dry naturally if this happens until it returns to normal size.
Always check your medication manufacturer’s storage guidelines and visually inspect your adrenaline or insulin before use.
EPIPEN is a registered trademark of Mylan Inc., which does not sponsor or endorse this product.
FAQ Section
Q1. How long does a FRIO insulated epipen case keep my medication cool?
FRIO Coolers keep your adrenaline pens within a safe temperature range of approximately 18–26°C for a minimum of 45 hours, even in ambient temperatures up to 37.8°C.
Q2. Do I need ice packs or a fridge for my FRIO wallet?
No – FRIO coolers use water‑activated crystals to provide evaporative cooling, so you do not need ice, gels or electricity.
Q3. How do I activate the FRIO Coolers – Insulated EpiPen Case?
Submerge the inner FRIO wallet in cold water for around 5–10 minutes, gently blot away excess water with a paper towel and then insert your adrenaline pens or other medication.
Q4. Which size FRIO epipen case should I choose?
Choose Small for 1 auto‑injector, Grande for 2 auto‑injectors, or Large for up to 3 EPIPEN/Anapen/Jext or 2 Auvi‑Q/Allerject pens and extra medication such as insulin or Humira pens. Read for more information Best EpiPen Cases for Kids & Adults – Safe Storage for Travel & Everyday Use (2026 Guide)
Q5. Can I store other medicines in the FRIO wallet?
Yes, FRIO coolers are suitable for many temperature‑sensitive medicines including insulin, Humira, Enbrel and similar injectable medication, provided you follow the manufacturer’s storage guidance.
Q6. Is the FRIO wallet waterproof?
The FRIO wallet is water‑resistant but not fully waterproof; use a waterproof liner for metal pens or electronics and avoid full immersion when activated.
Q7. How often can I reuse my FRIO cooling wallet?
With correct use and drying between activations, a FRIO insulated epipen case is reusable many times and designed for long‑term travel and everyday use.
N.B. This product & packaging was originally designed for carrying insulin pens but is suitable for carrying all kinds of temperature sensitive medicines including adrenaline pens, insulin pens, Humira pens and Enbrel pens.
Note: It is important that the immersion time is strictly monitored and adhered to so that the correct amount of water is absorbed. Over-soaking can render the wallet unusable. Should this occur, the wallet must be allowed to dry naturally until it returns to a usable size.
EPIPEN® is a registered trademark of Mylan Inc. Mylan Inc. does not sponsor or endorse the products referenced or sold on these web pages.
Why Choose Allergy Lifestyle?
At Allergy Lifestyle, we understand the importance of reliable allergy management products. Our products are carefully selected to meet the needs of families, schools, and individuals managing severe allergies.
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Sara (verified owner) –
Excellent product! Keeps the temperature at recommended level!
Elise –
Great product and easy delivery
Stacey Hancock (verified owner) –
This product is brilliant , I was so worried about how I was going to keep my sons Epi pen cool whilst in the theme parks in Florida and so thankful I stumbled across this gem of a product, it’s so easy and simple to use . As stated on instructions simply put in cold water and the beads swell up and it keeps the pens at room temp. I only needed to refresh briefly every 3rd-4th day. It really is brilliant. It was scent free and sat nicely in the little back pocket of my 10year olds day pack and survived beast heat 36• during the magic kingdom parade so it gets my full approval . A must buy for epi pens when travelling abroad
Adrian Smith (verified owner) –
Really pleased with the large size. Kept the Epipens lovely and cool and would definitely recommend to anyone. Surprised how long it did stay cool.
Julie Woolford –
We have just got back from holiday 2 weeks in Florida (very hot) I was worried about my son’s EpiPen and come across this product it is fantastic couldn’t recommend it highly… it does last a long time cold we have been back a week and it’s still cold with not adding any more water.. very good
Amanda Slater (verified owner) –
Really pleased with these. Bought 2 grande packs to hold 2 jext pens each. They work really well and feel cool even in 35deg heat. Not long to reactivate either. I just set a reminder to do it every 2 days. Would definitely recommend them.
Eeva (verified owner) –
Excellent product!
It easy and simle to use.
Lynsey higham (verified owner) –
Very pleased , gel beads swell up really big providing good cushioning and stays cool for days ! Very good product
Greta (verified owner) –
Wonderful. My 13 year old son took it to China, with 35-40 degrees, and learnt to use it instantly. Planning some more travelling to really hot places now! Thank you
Tracey Hayfield (verified owner) –
Great product, used in Spain recently where it was very hot, knowing the anapens were safe in the heat gave us great peace of mind! Would definitely recommend!
Janie prince (verified owner) –
Great pouch and kept my 2 epipens cool in the Costa Rica heat. One small point though, the part which swells can overswell if you leave for tools g and then you can’t get both pens in and shut the pouch!
Kirsty Roberts (verified owner) –
Just what we were searching for. Kept my sons Epi pens cool and safe whilst on holiday in Barbados
Cleo Griffin (verified owner) –
Spent two weeks in France with temperatures over 35 degrees. Frio cases kept Anapens perfect. Easy to use, would highly recommend them.
Andrea (verified owner) –
Just back from 2 weeks in a very hot (up to 35 degrees) sticky and humid Florida, couldn’t have managed it without the frio pouch! Worked absolutely perfectly! Made our holiday a lot more relaxed knowing that our daughters epi-pens were safely stored!! Thanks so much
Joanne Bell (verified owner) –
This is an excellent product. Recently used on our first holiday abroad with my son. There was no shade on the beach but this ensured his jext pens stayed at the correct temperature and I didn’t need to worry. The most important thing I took away, don’t know what we would have done without it. Also very easy to use. Thank you
Natascha –
I am very pleased with the case, there are room for 3 epipen. It’s easy to make the preparations form use and I love that I don’t have to worry about the pens getting to warm
Alyssa (verified owner) –
Product worked great for my son’s EpiPens for a week at the beach.
My only recommendation is read the set-up instructions as it takes a little lead time to get ready. It’s EASY to prep but you can’t just walk out the door the first time you’re ready to use.
Get this product NOW and feel assured.
Andrew Heap (verified owner) –
Working well in 40C temperatures. Simple and effective, even in a v. hot parked car.
Tina (verified owner) –
I sent this with my son on camping trips in near 100 weather and it worked perfectly. Thank you for a product that reassures us that his epi-pen will be OK and usable should he need it in hot weather.
Annette Sullivan (verified owner) –
Bought this for my holidays in France in June for my son’s epipens. I tried it out at home and it kept the pens cool for the recommended time. It will put my mind at ease going to the beach and day trips in France. Excellent product.