The Ultimate Ice-Free EpiPen Cooling Travel Case
Protecting your life-saving medication shouldn’t stop you from exploring. The FRIO Insulated Zipper Wallet is the world’s first patented evaporative cooling system designed to keep your EpiPen and adrenaline autoinjectors safe and at the correct temperature for up to 45 hours. Winner of the prestigious UK Outdoor Industries Product of the Year Award, this cooling case is a must-have for daily commutes, hot beach days, and long-distance travel.
How the FRIO Evaporative Cooling Technology Works
Unlike bulky, heavy hard cases that rely on ice packs (which quickly melt and can freeze your medication), the FRIO wallet utilizes natural evaporative cooling.
Simple Activation: Just submerge the inner pouch in cold water for 5 to 10 minutes.
The Science: Special crystals inside the wallet absorb the water and activate into a cool gel.
Continuous Coolness: As the trapped water slowly evaporates, it naturally keeps your medication at a safe, stable temperature—even in scorching hot environments exceeding 30°C. To reuse, simply soak the wallet again to reactivate the gel!
Versatile Storage Capacity
Though originally engineered for insulin pens, this large-size zipper wallet is incredibly versatile. It safely accommodates:
Up to 3 adrenaline autoinjectors (EpiPen, Jext, or Anapen)
Up to 2 Auvi-Q or Allerject injectors
Up to 3 Humira® pens or 4 Enbrel® pens
Up to 5 standard-sized prefilled insulin injection pens
Designed for Daily Use and Adventure
Every FRIO Zipper Wallet includes a two-part system: an inner active cooling pouch and a rugged, zipped outer cover. The zip-top closure keeps your pens secure, while the outer material allows essential airflow for the evaporation process. It is lightweight, fits seamlessly into hand luggage, and provides absolute peace of mind wherever you go.
N.B. This product & packaging was originally designed for carrying insulin pens but is suitable for carrying all kinds of temperature sensitive medicines including adrenaline pens, Humira® pens and Enbrel® pens.
Note: We recommend that a waterproof liner is used with metal pens or with any electronic timing device or any accessory with electronic components to protect it from moisture.
EPIPEN® is a registered trademark of Mylan Inc. Mylan Inc. does not sponsor or endorse the products referenced or sold on these web pages.
Note: It is important that the immersion time is strictly monitored and adhered to so that the correct amount of water is absorbed. Over-soaking can render the wallet unusable. Should this occur, the wallet must be allowed to dry naturally until it returns to a usable size.











Marion (verified owner) –
I recently bought this product for a trip to Europe, it held 2 EpiPens and an Entyvio injection. It kept everything cool during the flight and remained cool for ages. It was light weight and easy to carry in my hand luggage, perfect for travelling with medication.
Sonja (verified owner) –
Keeps meds cool during hot days (30+ degrees Celcius), easy to use – after initial soaking less than 10 minutes a day – and the instructions are very clear.
C (verified owner) –
I spent an entire day at the beach (30-35 degrees Celcius), and the product kept my meds cool. Other items in my backpack were hot but I could feel the epipens being cool and safe inside the case.
Gill Morton (verified owner) –
I used this for the first time over Easter weekend and I was amazed how long the gel pack stayed cool. Excellent product.